Appendix 1 – Data files
These files are available in the Supplementary Materials folder, inside the main zip file submission.
Table 3: Supplementary files list, describing source, type, content and location.
Original experiment
Raw
Gene expression data.
E-GEOD-61141-raw-counts.tsv
Original experiment
Statistical analysis
Differential genetic expression data, represented as foldchange with significance p-values.
E-GEOD-61141-analytics.tsv
Original experiment
Experiment design
Tabulated 2D description of the original experiment setup
E-GEOD-61141-experiment-design.tsv
This research
Selected genes
Expression data of target genes, sample sets α,β,γ,δ.
E-GEOD-61141-raw-counts_graphs.xlsx → “target genes”
This research
Comparison pairs – first order
Differential genetic expression data, comparison Sets A,B,C,D.
E-GEOD-61141-raw-counts_graphs.xlsx → [gene name]
This research
Statistical analysis
Stat analysis of DGE of Sets A,B,C,D.
E-GEOD-61141-raw-counts_graphs.xlsx → [gene name]
This research
Comparison sets – second order
Comparison of foldchanges of each individual gene across all sets (e.g. STAT2 in Set C vs Set D vs Set A vs Set B); Comparison of foldchanges of each gene within each set (e.g. STAT2 vs OAS1 vs OAS2 vs OAS3 in Set B).
E-GEOD-61141-raw-counts_graphs.xlsx → “Comparison”
This research
Image
Fig 1a: Gene expression query sorted by foldchange in Excel.
Fig-1a_Results_Phase1_gene_selection _excel_sort_foldchange.png
This research
Image
Fig 1b: Gene expression query sorted by p-value in Excel.
Fig-1b_Results_Phase1_gene _selection_excel_sort_p-val.png
This research
Image
Fig. 2: Bar chart of DGE foldchange comparison.
Fig-2_Results_Phase2_Chart_DGE _ratios_annotated.png
This research
Image
Fig. 5: Flowchart of simplified OAS-RNaseL pathway to apoptosis with indication of non-RNaseL antiviral pathway.
Fig-5_Discussion_Phase3_Flowchart _of_OAS_activation_chains.png
Last updated